Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGAV | P06756 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | CASR | P41180 | 10/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472919 | 0.91 | ITGB3 (0.40) | ITGB3ITGAVITGA2BCASRDGAT2 | |
| SCHEMBL7464276 | 0.90 | ITGB3 (0.40) | ITGB3ITGAVITGA2BCASRDGAT2 | |
| SCHEMBL7470480 | 0.83 | ITGB3 (0.54) | ITGB3ITGAVITGA2BCASR | |
| SCHEMBL7048411 | 0.83 | ITGB3 (0.51) | ITGB3ITGAVITGA2BCASRDGAT2 | |
| SCHEMBL7470398 | 0.83 | ITGB3 (0.51) | ITGB3ITGAVITGA2BCASRDGAT2 | |
| SCHEMBL7464586 | 0.81 | ITGB3 (0.40) | ITGB3ITGAVITGA2BCASRKDM4E | |
| SCHEMBL7462239 | 0.81 | ITGB3 (0.49) | ITGB3ITGAVITGA2BCASRKDM4E | |
| SCHEMBL7468320 | 0.80 | ITGB3 (0.43) | ITGB3ITGAVITGA2BCASRDGAT2 | |
| SCHEMBL7466616 | 0.80 | ITGB3 (0.44) | ITGB3ITGAVITGA2BCASRDGAT2 | |
| SCHEMBL7476304 | 0.80 | KDM4E (0.44) | ITGB3ITGAVITGA2BCASRDGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | claimed |
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |