Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467864 | 0.88 | HCRTR2 (0.33) | HCRTR2S1PR1S1PR3DHODHPDE2A | |
| SCHEMBL8492827 | 0.79 | HPGD (0.39) | DHODH | |
| SCHEMBL7464239 | 0.77 | DHODH (0.32) | DHODHPDE2A | |
| SCHEMBL7462608 | 0.77 | STAT3 (0.35) | DHODHPDE2A | |
| SCHEMBL9113812 | 0.75 | SMN1; SMN2 (0.33) | DHODHPDE2A | |
| SCHEMBL7469824 | 0.74 | TSHR (0.42) | DHODH | |
| Hydrochloric Acid SCHEMBL7464266 | 0.73 | TSHR (0.41) | DHODH | |
| SCHEMBL7464261 | 0.73 | KMT2A (0.34) | — | |
| SCHEMBL8605928 | 0.73 | DHODH (0.36) | DHODHPDE2A | |
| SCHEMBL8752752 | 0.73 | DHODH (0.36) | DHODHPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636622-B1 | Isoxazole derivatives and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-23 | — | — | EP | claimed |
| US-5489570-A | PRE- OR POST-EMERGENCE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-02-06 | — | — | US | claimed |
| EP-0636622-A1 | Isoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-02-01 | — | — | EP | claimed |
| EP-0636622-B1 | Isoxazole derivatives and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-23 | — | — | EP | disclosed |
| EP-1160244-A1 | Isoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LIMITED (GB) | 2001-12-05 | — | — | EP | disclosed |
| US-5489570-A | PRE- OR POST-EMERGENCE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-02-06 | — | — | US | disclosed |
| EP-0636622-A1 | Isoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-02-01 | — | — | EP | disclosed |