Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469824 | 0.88 | TSHR (0.42) | KMT2AKDM4ETSHRHSD17B10CYP3A4 | |
| Hydrochloric Acid SCHEMBL7464266 | 0.87 | TSHR (0.41) | KMT2AKDM4ETSHRHSD17B10CYP3A4 | |
| SCHEMBL7466592 | 0.86 | CA12 (0.40) | KMT2AKDM4EMAPTTSHRHSD17B10 | |
| SCHEMBL7462861 | 0.84 | KMT2A (0.38) | KMT2AKDM4EMAPTTSHRCYP3A4 | |
| SCHEMBL7465160 | 0.79 | MAPT (0.33) | KMT2AMAPTALDH1A1 | |
| SCHEMBL7476511 | 0.76 | TSHR (0.40) | KMT2AKDM4EMAPTTSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL7462872 | 0.75 | TSHR (0.39) | KMT2AKDM4EMAPTTSHRHSD17B10 | |
| SCHEMBL7467609 | 0.74 | — | — | |
| SCHEMBL7467904 | 0.74 | CA12 (0.41) | KMT2AKDM4EMAPTTSHRHSD17B10 | |
| SCHEMBL7469191 | 0.73 | HCRTR2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636622-B1 | Isoxazole derivatives and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-23 | — | — | EP | disclosed |
| EP-1160244-A1 | Isoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LIMITED (GB) | 2001-12-05 | — | — | EP | disclosed |
| US-5489570-A | PRE- OR POST-EMERGENCE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-02-06 | — | — | US | disclosed |
| EP-0636622-A1 | Isoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-02-01 | — | — | EP | disclosed |