Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 11/20 | 0.67 |
| ▸ | GSK3A | P49840 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5457426 | 0.82 | GSK3A (0.68) | KCNN4GSK3AGSK3BALDH1A1POLB | |
| SCHEMBL17007596 | 0.81 | KCNN4 (1.00) | KCNN4 | |
| SCHEMBL17015105 | 0.81 | KCNN4 (1.00) | KCNN4CHRM5HCRTR1HCRTR2 | |
| SCHEMBL5461421 | 0.80 | KCNN4 (0.65) | KCNN4GSK3AGSK3BALDH1A1POLB | |
| SCHEMBL26710431 | 0.80 | GSK3A (0.65) | KCNN4GSK3AGSK3BALDH1A1POLB | |
| SCHEMBL17015104 | 0.79 | KCNN4 (1.00) | KCNN4CHRM5 | |
| SCHEMBL7460972 | 0.78 | GSK3A (0.67) | KCNN4GSK3AGSK3BALDH1A1POLB | |
| SCHEMBL17015112 | 0.77 | KCNN4 (1.00) | KCNN4CHRM5HCRTR1HCRTR2 | |
| SCHEMBL5455026 | 0.75 | GSK3A (0.67) | KCNN4GSK3AGSK3BALDH1A1POLB | |
| SCHEMBL5782807 | 0.75 | GSK3A (0.67) | KCNN4GSK3AGSK3BALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214305-A1 | BENZYLIDENE-THIAZOLIDINEDIONES AND ANALOGUES AND THEIR USE IN THE TREATMENT OF INFLAMMATION | Maxia Pharmaceuticals, Inc. (US) | 2002-06-19 | — | — | EP | claimed |
| WO-2001016123-A1 | BENZYLIDENE-THIAZOLIDINEDIONES AND ANALOGUES AND THEIR USE IN THE TREATMENT OF INFLAMMATION | MAXIA PHARMACEUTICALS, INC. (US) | 2001-03-08 | — | — | WO | claimed |