Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.67 |
| ▸ | GSK3B | P49841 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | KCNN4 | O15554 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462946 | 0.85 | GSK3A (0.67) | GSK3AGSK3BALDH1A1POLBPIM1 | |
| SCHEMBL5455026 | 0.82 | GSK3A (0.67) | GSK3AGSK3BALDH1A1POLBPIM1 | |
| SCHEMBL5782807 | 0.82 | GSK3A (0.67) | GSK3AGSK3BALDH1A1POLBPIM1 | |
| SCHEMBL5455104 | 0.82 | GSK3A (0.71) | GSK3AGSK3BALDH1A1POLBPIM1 | |
| SCHEMBL29411719 | 0.82 | ALDH1A1 (0.68) | GSK3AGSK3BALDH1A1POLBPIM1 | |
| SCHEMBL5461421 | 0.81 | KCNN4 (0.65) | GSK3AGSK3BALDH1A1POLBKCNN4 | |
| SCHEMBL7463278 | 0.81 | GSK3A (0.61) | GSK3AGSK3BALDH1A1POLBPIM1 | |
| Hydrochloric Acid SCHEMBL5460366 | 0.81 | GSK3A (0.65) | GSK3AGSK3BALDH1A1POLBPIM1 | |
| SCHEMBL338442 | 0.80 | GSK3A (1.00) | GSK3AGSK3BALDH1A1POLBPIM1 | |
| SCHEMBL1200938 | 0.78 | ALDH1A1 (1.00) | GSK3AGSK3BALDH1A1POLBHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214305-A1 | BENZYLIDENE-THIAZOLIDINEDIONES AND ANALOGUES AND THEIR USE IN THE TREATMENT OF INFLAMMATION | Maxia Pharmaceuticals, Inc. (US) | 2002-06-19 | — | — | EP | claimed |
| WO-2001016123-A1 | BENZYLIDENE-THIAZOLIDINEDIONES AND ANALOGUES AND THEIR USE IN THE TREATMENT OF INFLAMMATION | MAXIA PHARMACEUTICALS, INC. (US) | 2001-03-08 | — | — | WO | claimed |
| EP-1214305-A1 | BENZYLIDENE-THIAZOLIDINEDIONES AND ANALOGUES AND THEIR USE IN THE TREATMENT OF INFLAMMATION | Maxia Pharmaceuticals, Inc. (US) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001016123-A1 | BENZYLIDENE-THIAZOLIDINEDIONES AND ANALOGUES AND THEIR USE IN THE TREATMENT OF INFLAMMATION | MAXIA PHARMACEUTICALS, INC. (US) | 2001-03-08 | — | — | WO | disclosed |