Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469479 | 1.00 | TDP1 (0.48) | TDP1MEN1KMT2AMAPTMCL1 | |
| SCHEMBL7466689 | 0.84 | TDP1 (0.53) | TDP1MEN1KMT2AMAPTMCL1 | |
| SCHEMBL1086730 | 0.80 | ELANE (0.51) | TDP1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL29539680 | 0.80 | ELANE (0.51) | TDP1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL1643210 | 0.80 | ELANE (0.51) | TDP1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL318267 | 0.75 | TDP1 (0.44) | TDP1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL318266 | 0.75 | TDP1 (0.44) | TDP1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL8105291 | 0.74 | TDP1 (0.39) | TDP1MCL1PTPN1ALOX5 | |
| Water SCHEMBL8747691 | 0.73 | TDP1 (0.38) | TDP1 | |
| Thiophene SCHEMBL28940616 | 0.73 | ELANE (0.45) | TDP1MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771796-B1 | Substituted S-triazines and process for their preparation | AGFA GEVAERT (BE) | 2002-06-19 | — | — | EP | disclosed |
| EP-0771796-A1 | Substituted S-triazines and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-07 | — | — | EP | disclosed |