SCHEMBL8105291

SCHEMBL8105291

C(=Cc1nc2c(ccc3ccccc32)o1)C=C1Nc2ccccc2O1

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.39
ALOX5 P09917 1/20 0.33
MCL1 Q07820 1/20 0.32
DHODH Q02127 1/20 0.32
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9011848 0.95 TDP1 (0.40) TDP1ALOX5MCL1DHODH
Water SCHEMBL8747691 0.85 TDP1 (0.38) TDP1
Water SCHEMBL9843388 0.81 ALOX5 (0.33) ALOX5DHODH
Naphthalene SCHEMBL9806048 0.81 SNCA (0.46) ALOX5DHODH
SCHEMBL4755956 0.81 SNCA (0.48) ALOX5DHODH
SCHEMBL75983 0.81 SNCA (0.48) ALOX5DHODH
Naphthalene SCHEMBL16150068 0.80 SNCA (0.45) ALOX5DHODH
SCHEMBL7922534 0.80 SNCA (0.47) ALOX5DHODH
Water SCHEMBL9843599 0.80 SNCA (0.47) ALOX5DHODH
Water SCHEMBL10771784 0.79 SNCA (0.46) ALOX5DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0930527-A1 Radiographic intensifying screen-film combination AGFA-GEVAERT N.V. (BE) 1999-07-21 EP claimed
US-6066441-A DEVELOPING, FIXING, RINSING AND DRYING USING AN ASCORBIC ACID TYPE DEVELOPER AND AN EQUIVALENT DEVELOPER REPLENISHER PROVIDING A REGENERATION AMOUNT OF LESS THAN 150 ML/M2, HAVING BUFFERING CAPACITY LESS THAN 6 MMOLE/M2 AGFA-GEVAERT, N.V. (BE) 2000-05-23 US disclosed
EP-0962820-A1 Processing of radiographic materials having emulsion grains rich in silver chloride AGFA-GEVAERT N.V. (BE) 1999-12-08 EP disclosed
EP-0930527-A1 Radiographic intensifying screen-film combination AGFA-GEVAERT N.V. (BE) 1999-07-21 EP disclosed
EP-0930527-A1 Radiographic intensifying screen-film combination AGFA-GEVAERT N.V. (BE) 1999-07-21 EP disclosed
US-5028522-A High speed, storage stable, nonfogging, selenium compounds FUJI PHOTO FILM CO., LTD. (JP) 1991-07-02 US disclosed
US-3977882-A CARBOCYANINE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-08-31 US disclosed