Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.44 |
| ▸ | ITGAV | P06756 | 6/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464674 | 0.92 | ITGB3 (0.45) | ITGB3ITGAVITGA2BKDM4EALDH1A1 | |
| SCHEMBL7457808 | 0.92 | ITGB3 (0.45) | ITGB3ITGAVITGA2BKDM4EALDH1A1 | |
| SCHEMBL381838 | 0.91 | ITGB3 (0.51) | ITGB3ITGAVITGA2BPARP1P2RY12 | |
| SCHEMBL7470398 | 0.89 | ITGB3 (0.51) | ITGB3ITGAVITGA2BCCR2KDM4E | |
| SCHEMBL7048411 | 0.89 | ITGB3 (0.51) | ITGB3ITGAVITGA2BCCR2KDM4E | |
| SCHEMBL7474930 | 0.88 | ITGB3 (0.43) | ITGB3ITGAVITGA2BCCR2KDM4E | |
| SCHEMBL7469429 | 0.88 | ITGB3 (0.43) | ITGB3ITGAVITGA2BCCR2KDM4E | |
| SCHEMBL7465113 | 0.87 | ITGB3 (0.45) | ITGB3ITGAVITGA2BCCR2HTT | |
| SCHEMBL7462239 | 0.86 | ITGB3 (0.49) | ITGB3ITGAVITGA2BCCR2KDM4E | |
| SCHEMBL7468383 | 0.86 | ITGB3 (0.41) | ITGB3ITGAVITGA2BCCR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | claimed |
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |