SCHEMBL7469617

SCHEMBL7469617

CC1(C)CC(N(CCNCCN)C2CC(C)(C)N(O)C(C)(C)C2)CC(C)(C)N1O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
ACE2 Q9BYF1 1/20 0.34
ALDH1A1 P00352 2/20 0.31
ALOX15 P16050 2/20 0.31
CA12 O43570 2/20 0.31
CA6 P23280 2/20 0.31
CA7 P43166 2/20 0.31
CA9 Q16790 2/20 0.31
CA14 Q9ULX7 2/20 0.31
CA5B Q9Y2D0 2/20 0.31
MEN1 O00255 1/20 0.31
RECQL P46063 1/20 0.31
KMT2A Q03164 1/20 0.31
GAA P10253 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
TDP1 Q9NUW8 3/20 0.30
LMNA P02545 2/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8789959 0.84 CYP2C9 (0.39) CYP2C9CYP2C19ACE2ALDH1A1ALOX15
Tempol Hydroxylamine SCHEMBL3946306 0.78 GAA (0.39) CYP2C9CYP2C19ACE2ALDH1A1ALOX15
SCHEMBL13202057 0.74 CA12 (0.37) ACE2ALDH1A1ALOX15CA12CA6
Tempol Hydroxylamine SCHEMBL27621676 0.72 GAA (0.34) ACE2ALDH1A1ALOX15CA12CA6
Tempol Hydroxylamine SCHEMBL2858010 0.72 GAA (0.34) ACE2ALDH1A1ALOX15CA12CA6
SCHEMBL27648896 0.71 GAA (0.45) ACE2ALDH1A1CA12CA6CA7
SCHEMBL5697706 0.69 GAA (0.39) KMT2AGAAL3MBTL1
Acetic Acid SCHEMBL27621684 0.69 KDM4E (0.43) ALOX15KMT2AGAA
Acetic Acid SCHEMBL2864226 0.69 KDM4E (0.43) ALOX15KMT2AGAA
SCHEMBL11203248 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1216269-A1 POLYMERIC STABILIZERS WITH HIGH AFFINITY TO PULP Ciba SC Holding AG (CH) 2002-06-26 EP disclosed
EP-1212486-A1 CHLOROHYDRIN AND CATIONIC COMPOUNDS HAVING HIGH AFFINITY FOR PULP OR PAPER Ciba SC Holding AG (CH) 2002-06-12 EP disclosed
WO-2001019897-A1 POLYMERIC STABILIZERS WITH HIGH AFFINITY TO PULP CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-03-22 WO disclosed
WO-2001020078-A1 CHLOROHYDRIN AND CATIONIC COMPOUNDS HAVING HIGH AFFINITY FOR PULP OR PAPER CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-03-22 WO disclosed