Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.61 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.56 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.56 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470197 | 0.88 | KCNH2 (0.61) | KCNH2DNMT1EHMT2HRH1CYP3A4 | |
| SCHEMBL7990886 | 0.84 | KCNH2 (0.53) | KCNH2DNMT1EHMT2HRH1DRD4 | |
| SCHEMBL7472545 | 0.84 | DNMT1 (0.58) | KCNH2DNMT1EHMT2HRH1CYP3A4 | |
| SCHEMBL7464967 | 0.82 | DNMT1 (0.54) | KCNH2DNMT1EHMT2HRH1CYP3A4 | |
| Hydrochloric Acid SCHEMBL8200558 | 0.82 | KCNH2 (0.67) | KCNH2DNMT1EHMT2HRH1CHRM4 | |
| SCHEMBL7469010 | 0.81 | DNMT1 (0.53) | KCNH2DNMT1EHMT2HRH1BCHE | |
| SCHEMBL7470504 | 0.81 | KCNH2 (0.52) | KCNH2DNMT1EHMT2HRH1BCHE | |
| SCHEMBL7467030 | 0.81 | DNMT1 (0.53) | KCNH2DNMT1EHMT2HRH1CYP3A4 | |
| SCHEMBL7995588 | 0.77 | DNMT1 (0.56) | KCNH2DNMT1EHMT2HRH1 | |
| SCHEMBL7472446 | 0.76 | DNMT1 (0.58) | KCNH2DNMT1EHMT2HRH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844825-B1 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4- BIS(SUBSTITUTED PHENYL OR PYRIDYL)METHYL]PIPERIDINES | FMC CORP (US) | 2002-11-27 | — | — | EP | claimed |
| EP-0844825-A4 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4- BIS(SUBSTITUTED PHENYL OR PYRIDYL)METHYL]PIPERIDINES | FMC CORP (US) | 2000-04-05 | — | — | EP | claimed |
| US-6030987-A | Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl or pyridyl)methyl]piperidines | FMC CORPORATION (US) | 2000-02-29 | — | — | US | claimed |
| EP-0844825-A1 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4- BIS(SUBSTITUTED PHENYL OR PYRIDYL)METHYL]PIPERIDINES | FMC CORPORATION (US) | 1998-06-03 | — | — | EP | claimed |
| WO-1996036228-A1 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4-[BIS(SUBSTITUTED PHENYL OR PYRIDYL)METHYL]PIPERIDINES | FMC CORPORATION (US) | 1996-11-21 | — | — | WO | claimed |