Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | ULK1 | O75385 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | EEF2K | O00418 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6734421 | 0.90 | MEP1B (0.39) | ULK1HDAC8HDAC6 | |
| SCHEMBL6734419 | 0.90 | MEP1B (0.39) | ULK1HDAC8HDAC6 | |
| SCHEMBL7467263 | 0.80 | SLC1A3 (0.38) | SLC1A3SLC1A2SLC1A1MAPTITGB3 | |
| SCHEMBL6741909 | 0.80 | CTNNB1 (0.41) | SLC1A3SLC1A2SLC1A1MAPTCA1 | |
| SCHEMBL12044424 | 0.76 | SLC1A3 (0.59) | SLC1A3SLC1A2SLC1A1MAPTITGB3 | |
| SCHEMBL6733224 | 0.76 | SLC1A3 (0.44) | SLC1A3SLC1A2SLC1A1MMP13CA2 | |
| SCHEMBL6733229 | 0.76 | SLC1A3 (0.44) | SLC1A3SLC1A2SLC1A1MMP13CA2 | |
| SCHEMBL7526081 | 0.72 | CTNNB1 (0.34) | SLC1A3SLC1A2SLC1A1MAPTCA1 | |
| SCHEMBL7059153 | 0.71 | CYP2A6 (0.38) | SLC1A3SLC1A2SLC1A1MMP13 | |
| SCHEMBL6740192 | 0.71 | HDAC1 (0.39) | HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244616-A1 | (HETERO)BICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED HYDROXAMIC ACID DERIVATIVES | SmithKline Beecham plc (GB) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001047874-A1 | (HETERO)BICYCLYMETHANESULFONYLAMINO-SUBSTITUTED HYDROXAMIC ACID DERIVATIVES | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-07-05 | — | — | WO | disclosed |