Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.46 |
| ▸ | MAT2A | P31153 | 1/20 | 0.45 |
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | IL1RN | P18510 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460037 | 0.99 | CMA1 (0.67) | CMA1CA9CA12AKR1C3AKR1C1 | |
| SCHEMBL7469742 | 0.89 | CMA1 (0.69) | CMA1CA9CA12AKR1C3AKR1C1 | |
| SCHEMBL7464440 | 0.88 | CMA1 (0.77) | CMA1CA9CA12ACLYCA1 | |
| SCHEMBL7461590 | 0.86 | CMA1 (0.79) | CMA1CA9CA12ACLYCA1 | |
| SCHEMBL7464965 | 0.85 | CMA1 (0.85) | CMA1CA9CA12CA1CA2 | |
| SCHEMBL3781496 | 0.84 | CMA1 (0.71) | CMA1CA9CA12CA1CA2 | |
| SCHEMBL3782983 | 0.83 | CMA1 (0.63) | CMA1CA9CA12CA1CA2 | |
| SCHEMBL3782209 | 0.82 | CMA1 (0.71) | CMA1CA9CA12CA1CA2 | |
| SCHEMBL3780426 | 0.82 | CMA1 (0.67) | CMA1CA9CA12CA1CA2 | |
| SCHEMBL7472700 | 0.81 | CMA1 (0.55) | CMA1CA9CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |