Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21657603 | 0.88 | TDP1 (0.57) | TDP1ALDH1A1TP53TSHRSMN1; SMN2 | |
| SCHEMBL8730031 | 0.88 | TDP1 (0.57) | TDP1ALDH1A1TP53TSHRSMN1; SMN2 | |
| SCHEMBL30628474 | 0.88 | TDP1 (0.57) | TDP1ALDH1A1TP53TSHRSMN1; SMN2 | |
| SCHEMBL8730039 | 0.88 | TDP1 (0.57) | TDP1ALDH1A1TP53TSHRSMN1; SMN2 | |
| SCHEMBL29721135 | 0.88 | TDP1 (0.57) | TDP1ALDH1A1TP53TSHRSMN1; SMN2 | |
| SCHEMBL8758115 | 0.84 | TDP1 (0.53) | TDP1ALDH1A1TP53TSHRSMN1; SMN2 | |
| SCHEMBL8758127 | 0.84 | TDP1 (0.53) | TDP1ALDH1A1TP53TSHRSMN1; SMN2 | |
| SCHEMBL7778474 | 0.83 | MAOB (0.59) | SMN1; SMN2HIF1ACYP3A4RAB9AMAOB | |
| SCHEMBL23403775 | 0.82 | TDP1 (0.54) | TDP1ALDH1A1TP53TSHRSMN1; SMN2 | |
| SCHEMBL7526730 | 0.82 | TDP1 (0.50) | TDP1ALDH1A1TP53TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087961-B1 | PHENOXYLPROPANOLAMINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI SYNTHELABO (FR) | 2002-08-14 | — | — | EP | disclosed |