Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TOP1 | P11387 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5901973 | 0.90 | MAOB (0.53) | MAOBALOX5RAB9ASMN1; SMN2LMNA | |
| SCHEMBL8184228 | 0.90 | MAOB (0.60) | MAOBALOX5LMNAHDAC6MAPT | |
| SCHEMBL30148511 | 0.90 | MAOB (0.60) | MAOBALOX5LMNAHDAC6MAPT | |
| SCHEMBL18623184 | 0.90 | MAOB (0.60) | MAOBRAB9ASMN1; SMN2HDAC6 | |
| SCHEMBL3229614 | 0.89 | RAB9A (0.51) | MAOBALOX5RAB9ASMN1; SMN2LMNA | |
| SCHEMBL3238141 | 0.88 | RAB9A (0.53) | MAOBALOX5RAB9ASMN1; SMN2LMNA | |
| SCHEMBL7606123 | 0.88 | MAOB (0.50) | MAOBALOX5RAB9ASMN1; SMN2HDAC6 | |
| SCHEMBL24244911 | 0.87 | GSTP1 (0.54) | MAOBALOX5RAB9ASMN1; SMN2LMNA | |
| SCHEMBL9430862 | 0.86 | MAOB (0.53) | MAOBALOX5RAB9ASMN1; SMN2LMNA | |
| SCHEMBL10469385 | 0.86 | RAB9A (0.49) | MAOBALOX5RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121125-A1 | PHARMACEUTICAL FORMULATIONS FOR USE IN ESTROGEN DEPRIVATION SYNDROME | ELI LILLY AND COMPANY (US) | 2001-08-08 | — | — | EP | claimed |
| WO-2000021535-A1 | PHARMACEUTICAL FORMULATIONS FOR USE IN ESTROGEN DEPRIVATION SYNDROME | ELI LILLY AND COMPANY (US) | 2000-04-20 | — | — | WO | claimed |