Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 14/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 12/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ATF4 | P18848 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7458989 | 0.91 | HRH3 (0.43) | ADRB3ADRB1ADRB2CYP3A4CYP2D6 | |
| SCHEMBL6139617 | 0.90 | ADRB3 (0.41) | ADRB3ADRB1ADRB2CYP3A4CYP2D6 | |
| SCHEMBL6139574 | 0.89 | ALDH1A1 (0.46) | ADRB3ADRB1ADRB2LMNA | |
| SCHEMBL6139717 | 0.83 | HSD17B10 (0.40) | ADRB3 | |
| SCHEMBL6139466 | 0.83 | ADRB3 (0.40) | ADRB3ADRB1ADRB2CYP3A4CYP2D6 | |
| SCHEMBL6140070 | 0.82 | ALDH1A1 (0.47) | LMNA | |
| SCHEMBL5206634 | 0.82 | CYP3A4 (0.44) | ADRB3ADRB1ADRB2CYP3A4CYP2D6 | |
| SCHEMBL6139691 | 0.82 | ALDH1A1 (0.44) | ADRB3ADRB1ADRB2 | |
| SCHEMBL5208641 | 0.82 | ADRB3 (0.44) | ADRB3ADRB1ADRB2CYP3A4CYP2D6 | |
| SCHEMBL5203201 | 0.81 | ADRB3 (0.42) | ADRB3ADRB1ADRB2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087961-B1 | PHENOXYLPROPANOLAMINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI SYNTHELABO (FR) | 2002-08-14 | — | — | EP | disclosed |