SCHEMBL7470077

SCHEMBL7470077

CCC(C)(C)C(=O)C(=O)N1CCC[C@H]1CS(=O)(=O)C(CCc1cccnc1)CCc1cccnc1

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 16/20 0.58
MTOR P42345 1/20 0.58
FKBP4 Q02790 1/20 0.58
FKBP5 Q13451 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7561500 0.89 FKBP1A (0.49) FKBP1AMTORFKBP4FKBP5
SCHEMBL7468444 0.87 FKBP1A (0.63) FKBP1AMTORFKBP4FKBP5
SCHEMBL7470890 0.82 FKBP1A (0.47) FKBP1AMTORFKBP4FKBP5
SCHEMBL7470088 0.80 FKBP1A (0.53) FKBP1AMTORFKBP4FKBP5
SCHEMBL8204783 0.79 FKBP1A (0.73) FKBP1AMTORFKBP4FKBP5
SCHEMBL7469115 0.79 FKBP1A (0.47) FKBP1A
SCHEMBL7463760 0.78 FKBP1A (0.62) FKBP1AFKBP4FKBP5
SCHEMBL7460552 0.78 FKBP1A (0.63) FKBP1AMTORFKBP4FKBP5
SCHEMBL10034623 0.77 FKBP1A (0.72) FKBP1AMTORFKBP4FKBP5
SCHEMBL10034615 0.76 FKBP1A (0.70) FKBP1AMTORFKBP4FKBP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1204657-A1 PIPERIDINE AND PYRROLIDINE DERIVATIVES DISPLAYING NEURONAL ACTIVITY SCHERING AKTIENGESELLSCHAFT (DE) 2002-05-15 EP claimed
WO-2001012622-A1 PIPERIDINE AND PYRROLIDINE DERIVATIVES DISPLAYING NEURONAL ACTIVITY SCHERING AKTIENGESELLSCHAFT (DE) 2001-02-22 WO claimed
EP-1204657-A1 PIPERIDINE AND PYRROLIDINE DERIVATIVES DISPLAYING NEURONAL ACTIVITY SCHERING AKTIENGESELLSCHAFT (DE) 2002-05-15 EP disclosed
WO-2001012622-A1 PIPERIDINE AND PYRROLIDINE DERIVATIVES DISPLAYING NEURONAL ACTIVITY SCHERING AKTIENGESELLSCHAFT (DE) 2001-02-22 WO disclosed