SCHEMBL74701

SCHEMBL74701

O=c1c(O)c(-c2ccccc2)oc2cc3oc(-c4ccccc4)c(O)c(=O)c3cc12

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 11/20 0.74
MEN1 O00255 11/20 0.74
KMT2A Q03164 11/20 0.74
KDM4E B2RXH2 9/20 0.74
MAPT P10636 8/20 0.74
HSD17B10 Q99714 8/20 0.74
ALOX15 P16050 5/20 0.74
CASP1 P29466 2/20 0.74
CASP7 P55210 2/20 0.74
MAPK1 P28482 5/20 0.73
TP53 P04637 5/20 0.73
LMNA P02545 3/20 0.73
CA12 O43570 2/20 0.73
ABCB1 P08183 2/20 0.73
CYP1B1 Q16678 2/20 0.73
CA1 P00915 1/20 0.73
CA2 P00918 1/20 0.73
CALM1 P0DP23 1/20 0.73
AR P10275 1/20 0.73
PKM P14618 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25206362 0.90 KDM4E (0.70) CYP3A4MEN1KMT2AKDM4EMAPT
SCHEMBL17940142 0.89 CYP3A4 (0.68) CYP3A4MEN1KMT2AKDM4EMAPT
SCHEMBL25236328 0.87 KDM4E (0.67) CYP3A4MEN1KMT2AKDM4EMAPT
3,7-Dihydroxyflavone SCHEMBL2396684 0.85 CYP3A4 (1.00) CYP3A4MEN1KMT2AKDM4EMAPT
3,7-Dihydroxyflavone SCHEMBL29625323 0.85 CYP3A4 (1.00) CYP3A4MEN1KMT2AKDM4EMAPT
SCHEMBL15456750 0.85 CYP3A4 (0.82) CYP3A4MEN1KMT2AKDM4EMAPT
SCHEMBL1627936 0.85 CYP3A4 (0.82) CYP3A4MEN1KMT2AKDM4EMAPT
Flavonol SCHEMBL29433939 0.84 KDM4E (1.00) CYP3A4MEN1KMT2AKDM4EMAPT
Flavonol SCHEMBL20246 0.84 KDM4E (1.00) CYP3A4MEN1KMT2AKDM4EMAPT
Flavonol SCHEMBL1679068 0.84 KDM4E (1.00) CYP3A4MEN1KMT2AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3713925-B1 SYNTHESIS OF MORIN AND MORIN DERIVATIVES ORSATEC GMBH (DE) 2026-04-22 EP claimed
US-8178702-B2 Composition, method of authenticating, methods of making authenticatable compositions, authenticatable articles made there from SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-05-15 US claimed
US-20080265176-A1 COMPOSITION, METHOD OF AUTHENTICATING, METHODS OF MAKING AUTHENTICATABLE COMPOSITIONS, AUTHENTICATABLE ARTICLES MADE THERE FROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2008-10-30 US claimed
US-20060131761-A1 Composition, method of authenticating, methods of making authenticatable compositions, authenticatable articles made there from SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2006-06-22 US claimed
CN-114736921-B Method for obtaining genetically transformed plant by utilizing iris DFR gene 宁夏大学 2023-12-29 CN disclosed
WO-2022113047-A1 4'-SUBSTITUTED ANALOGUES OF FISETIN AND THEIR USE IN THE TREATMENT OF CANCER STELLENBOSCH UNIVERSITY (ZA) 2022-06-02 WO disclosed
EP-2519584-B1 POLYCARBONATE-POLY(ETHER-ESTER) COPOLYMER COMPOSITION, METHOD OF MANUFACTURE, AND ARTICLES THEREFROM SABIC INNOVATIVE PLASTICS IP (NL) 2014-08-27 EP disclosed
US-8759428-B2 Polycarbonate compositions SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-06-24 US disclosed
US-8759428-B2 Polycarbonate compositions SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-06-24 US disclosed
EP-2519584-A1 POLYCARBONATE-POLY(ETHER-ESTER) COPOLYMER COMPOSITION, METHOD OF MANUFACTURE, AND ARTICLES THEREFROM SABIC Innovative Plastics IP B.V. (NL) 2012-11-07 EP disclosed
US-8178702-B2 Composition, method of authenticating, methods of making authenticatable compositions, authenticatable articles made there from SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-05-15 US disclosed
US-8129471-B2 Polycarbonate-poly(ether-ester) copolymer composition, method of manufacture, and articles therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-03-06 US disclosed
US-20110155975-A1 POLYCARBONATE-POLY(ETHER-ESTER) COPOLYMER COMPOSITION, METHOD OF MANUFACTURE, AND ARTICLES THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2011-06-30 US disclosed
US-7635778-B2 For example, 3-ethylcarbonate-2-(4-(3-ethylcarbonate-4-oxo-4H-chromen-2-yl)phenyl)-4H-chromen-4-one; authentication markers for use in data storage media substrates SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-12-22 US disclosed
US-20090054586-A1 POLYCARBONATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2009-02-26 US disclosed
US-20090054586-A1 POLYCARBONATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2009-02-26 US disclosed
US-20080265176-A1 COMPOSITION, METHOD OF AUTHENTICATING, METHODS OF MAKING AUTHENTICATABLE COMPOSITIONS, AUTHENTICATABLE ARTICLES MADE THERE FROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2008-10-30 US disclosed
EP-1866842-A2 A COMPOSITION, METHOD OF AUTHENTICATING, METHODS OF MAKING AUTHENTICATABLE COMPOSITIONS, AUTHENTICATABLE ARTICLES MADE THERE FROM General Electric Company (US) 2007-12-19 EP disclosed
WO-2006065561-A2 A COMPOSITION, METHOD OF AUTHENTICATING, METHODS OF MAKING AUTHENTICATABLE COMPOSITIONS, AUTHENTICATABLE ARTICLES MADE THERE FROM GENERAL ELECTRIC COMPANY (US) 2006-06-22 WO disclosed
US-20060131761-A1 Composition, method of authenticating, methods of making authenticatable compositions, authenticatable articles made there from SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2006-06-22 US disclosed