Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470224 | 1.00 | HIF1A (0.49) | HIF1AMAOAMAOBNPC1RAB9A | |
| SCHEMBL7467513 | 0.93 | MAOB (0.41) | HIF1AMAOBNPC1RAB9ANR4A2 | |
| SCHEMBL7467515 | 0.93 | MAOB (0.41) | HIF1AMAOBNPC1RAB9ANR4A2 | |
| SCHEMBL17949969 | 0.93 | HIF1A (0.40) | HIF1ANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7463027 | 0.92 | HIF1A (0.40) | HIF1ANPC1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL7463026 | 0.92 | HIF1A (0.40) | HIF1ANPC1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL7465129 | 0.91 | MAOB (0.43) | HIF1AMAOBFFAR1 | |
| SCHEMBL7465132 | 0.91 | MAOB (0.43) | HIF1AMAOBFFAR1 | |
| SCHEMBL7863513 | 0.90 | HIF1A (0.41) | HIF1ASMN1; SMN2KDM4ETDP1L3MBTL1 | |
| SCHEMBL7863516 | 0.90 | HIF1A (0.41) | HIF1ASMN1; SMN2KDM4ETDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865424-B1 | PESTICIDES | BAYER AG (DE) | 2002-09-18 | — | — | EP | disclosed |
| US-6420423-B1 | PESTICIDE FOR USE ON CEREALS, BEETS, FRUITS, BERRIES, AND BEANS; KILLS MITES, INSECTS, TERMITES, LICE, FLEAS, AND FUNGUS; TOLERATED WELL BE ANIMALS, PLANTS, AND FISH | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-16 | — | — | US | disclosed |
| US-5985921-A | OXIDATION AND HYDROGENATION OF COMPOUNDS TO FORM INSECTICIDES AS AGROCHEMICALS | NOVARTIS CORPORATION (US) | 1999-11-16 | — | — | US | disclosed |
| EP-0865424-A1 | PESTICIDES | Novartis AG (CH) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020809-A1 | PESTICIDES | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |