SCHEMBL7465129

SCHEMBL7465129

CCO/N=C(C(/C)=N/OCc1ccccc1/C(=C\OC)C(=O)OC)\c1ccc(OCc2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.43
HIF1A Q16665 4/20 0.43
FFAR1 O14842 2/20 0.38
PPARG P37231 1/20 0.38
SLC6A5 Q9Y345 4/20 0.37
PPARA Q07869 1/20 0.37
SPHK2 Q9NRA0 1/20 0.37
SPHK1 Q9NYA1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7465132 1.00 MAOB (0.43) MAOBHIF1AFFAR1PPARGSLC6A5
SCHEMBL7470560 0.92 HIF1A (0.38) MAOBHIF1A
SCHEMBL7470567 0.92 HIF1A (0.38) MAOBHIF1A
SCHEMBL7465783 0.92 MAOB (0.47) MAOBHIF1AFFAR1SPHK2SPHK1
SCHEMBL7465781 0.92 MAOB (0.47) MAOBHIF1AFFAR1SPHK2SPHK1
SCHEMBL7462687 0.92 MAOB (0.47) MAOBHIF1AFFAR1SPHK2SPHK1
SCHEMBL7467513 0.92 MAOB (0.41) MAOBHIF1A
SCHEMBL7467515 0.92 MAOB (0.41) MAOBHIF1A
SCHEMBL7470221 0.91 HIF1A (0.49) MAOBHIF1AFFAR1
SCHEMBL7470224 0.91 HIF1A (0.49) MAOBHIF1AFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0865424-B1 PESTICIDES BAYER AG (DE) 2002-09-18 EP disclosed
US-6420423-B1 PESTICIDE FOR USE ON CEREALS, BEETS, FRUITS, BERRIES, AND BEANS; KILLS MITES, INSECTS, TERMITES, LICE, FLEAS, AND FUNGUS; TOLERATED WELL BE ANIMALS, PLANTS, AND FISH BAYER AKTIENGESELLSCHAFT (DE) 2002-07-16 US disclosed
US-5985921-A OXIDATION AND HYDROGENATION OF COMPOUNDS TO FORM INSECTICIDES AS AGROCHEMICALS NOVARTIS CORPORATION (US) 1999-11-16 US disclosed
EP-0865424-A1 PESTICIDES Novartis AG (CH) 1998-09-23 EP disclosed
WO-1997020809-A1 PESTICIDES NOVARTIS AG (CH) 1997-06-12 WO disclosed