Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 18/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13298912 | 0.92 | MIF (0.59) | MIFNPC1RAB9ASMN1; SMN2HDAC6 | |
| SCHEMBL3327267 | 0.90 | MIF (0.57) | MIFNPC1RAB9ASMN1; SMN2HDAC6 | |
| SCHEMBL7477204 | 0.88 | MIF (0.54) | MIFNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7464403 | 0.88 | MIF (0.53) | MIFNPC1RAB9ASMN1; SMN2HDAC6 | |
| SCHEMBL3325154 | 0.88 | MIF (0.55) | MIFNPC1RAB9ASMN1; SMN2HDAC6 | |
| SCHEMBL7475040 | 0.88 | MIF (0.55) | MIFNPC1RAB9ASMN1; SMN2HDAC6 | |
| SCHEMBL7463485 | 0.86 | POLB (0.53) | MIFNPC1RAB9ASMN1; SMN2HDAC6 | |
| SCHEMBL7463009 | 0.86 | MIF (0.53) | MIFRAB9A | |
| SCHEMBL7470274 | 0.85 | MIF (0.52) | MIFNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7502340 | 0.84 | MIF (0.51) | MIFNPC1RAB9ASMN1; SMN2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054874-B1 | SUBSTITUTED AMINOPHENYL ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS | UPJOHN CO (US) | 2002-08-28 | — | — | EP | disclosed |
| EP-1054874-A1 | SUBSTITUTED AMINOPHENYL ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 2000-11-29 | — | — | EP | disclosed |
| US-6069141-A | BACTERICIDES | PHARMACIA & UPJOHN COMPANY (US) | 2000-05-30 | — | — | US | disclosed |
| WO-1999041244-A1 | SUBSTITUTED AMINOPHENYL ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 1999-08-19 | — | — | WO | disclosed |