Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 9/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 2/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468943 | 0.91 | MAPK1 (0.46) | EGFRALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL7466238 | 0.91 | USP10 (0.48) | EGFRHTTLMNA | |
| SCHEMBL7468826 | 0.87 | EGFR (0.56) | EGFRALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL7469571 | 0.87 | EGFR (0.56) | EGFRALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL7475664 | 0.86 | EGFR (0.55) | EGFRALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL7466788 | 0.85 | PDE5A (0.57) | ALDH1A1MAPTTDP1HTTSMN1; SMN2 | |
| SCHEMBL7470206 | 0.84 | EGFR (0.52) | EGFRALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL7467033 | 0.84 | EGFR (0.52) | EGFRALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL7467456 | 0.84 | EGFR (0.52) | EGFRALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL7470361 | 0.82 | HTT (0.45) | HTTSMN1; SMN2NR2F2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |