Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.56 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473166 | 0.91 | HTR6 (0.55) | EGFRSIRT6ALDH1A1MAPTLMNA | |
| SCHEMBL7465055 | 0.91 | HTR6 (0.55) | EGFRSIRT6MAPTLMNAHTT | |
| SCHEMBL7475664 | 0.90 | EGFR (0.55) | EGFRALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL7467033 | 0.89 | EGFR (0.52) | EGFRALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL7467456 | 0.89 | EGFR (0.52) | EGFRALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL7468826 | 0.89 | EGFR (0.56) | EGFRALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL7470511 | 0.87 | EGFR (0.54) | EGFRALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL7459991 | 0.86 | LMNA (0.52) | EGFRALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL7464189 | 0.85 | MAPT (0.56) | ALDH1A1MAPTTDP1LMNAHTT | |
| SCHEMBL7470206 | 0.85 | EGFR (0.52) | EGFRALDH1A1MAPTTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |