Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 5/20 | 0.87 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.87 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.87 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.87 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | STAT3 | P40763 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13350317 | 0.93 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL7418696 | 0.93 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL7425456 | 0.93 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL7424183 | 0.81 | PDE4A (0.78) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL30305355 | 0.80 | ALDH1A1 (0.75) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL29019314 | 0.80 | ALDH1A1 (0.75) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL7423655 | 0.80 | PDE4A (0.77) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL7419331 | 0.80 | PDE4A (0.85) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL4788494 | 0.80 | CYP1A2 (0.78) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL31005217 | 0.80 | CYP1A2 (0.78) | PDE4APDE4BPDE4CPDE4DHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996036596-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | claimed |
| WO-1996036596-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | disclosed |