Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 17/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 11/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 19/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 14/20 | 0.48 |
| ▸ | OGFRL1 | Q5TC84 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7094375 | 0.85 | OPRM1 (0.64) | OPRL1OPRD1OPRM1OPRK1OGFRL1 | |
| SCHEMBL7091148 | 0.85 | OPRM1 (0.64) | OPRL1OPRD1OPRM1OPRK1OGFRL1 | |
| SCHEMBL7091438 | 0.85 | OPRM1 (0.64) | OPRL1OPRD1OPRM1OPRK1OGFRL1 | |
| SCHEMBL7092532 | 0.83 | OPRM1 (0.49) | OPRL1OPRD1OPRM1OPRK1OGFRL1 | |
| SCHEMBL7095250 | 0.83 | OPRM1 (0.64) | OPRL1OPRD1OPRM1OPRK1OGFRL1 | |
| SCHEMBL7095389 | 0.83 | OPRM1 (0.49) | OPRL1OPRD1OPRM1OPRK1OGFRL1 | |
| SCHEMBL7095822 | 0.83 | OPRM1 (0.64) | OPRL1OPRD1OPRM1OPRK1OGFRL1 | |
| SCHEMBL7095477 | 0.81 | OPRM1 (0.66) | OPRL1OPRD1OPRM1OPRK1OGFRL1 | |
| SCHEMBL7091290 | 0.81 | OPRM1 (0.66) | OPRL1OPRD1OPRM1OPRK1OGFRL1 | |
| SCHEMBL7091589 | 0.79 | OPRM1 (0.45) | OPRL1OPRD1OPRM1OPRK1OGFRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102762-B1 | 2-SUBSTITUTED-1-PIPERIDYL BENZIMIDAZOLE COMPOUNDS AS ORL1-RECEPTOR AGONISTS | PFIZER (US) | 2002-11-13 | — | — | EP | claimed |