Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 5/20 | 0.39 |
| ▸ | TDO2 | P48775 | 5/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460080 | 0.87 | IDO1 (0.49) | SLC6A4IDO1TDO2SLC6A2SLC6A3 | |
| SCHEMBL7466782 | 0.86 | SRD5A2 (0.45) | SLC6A4IDO1TDO2SRD5A2IDO2 | |
| SCHEMBL7460123 | 0.83 | IDO1 (0.51) | SLC6A4IDO1TDO2SRD5A2PGR | |
| SCHEMBL7471025 | 0.83 | F2 (0.41) | IDO1TDO2SRD5A2IDO2MEN1 | |
| SCHEMBL7461086 | 0.83 | CASR (0.42) | SRD5A2 | |
| SCHEMBL7466690 | 0.80 | IDO1 (0.55) | SLC6A4IDO1TDO2SLC6A2SLC6A3 | |
| SCHEMBL7455793 | 0.78 | SRD5A2 (0.39) | SLC6A4IDO1TDO2SRD5A2KMT2A | |
| SCHEMBL7461466 | 0.78 | PBRM1 (0.47) | ACP3SRD5A2PGR | |
| SCHEMBL7466995 | 0.75 | MAOB (0.41) | SRD5A2PGRFNTAFNTBMEN1 | |
| SCHEMBL7466731 | 0.74 | SLC6A4 (0.45) | SLC6A4IDO1TDO2SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244617-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-10-02 | — | — | EP | claimed |
| WO-2001047875-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-07-05 | — | — | WO | claimed |