Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.55 |
| ▸ | TDO2 | P48775 | 3/20 | 0.55 |
| ▸ | ACP3 | P15309 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466731 | 0.88 | SLC6A4 (0.45) | IDO1TDO2ACP3SLC6A2SLC6A4 | |
| SCHEMBL7466782 | 0.83 | SRD5A2 (0.45) | IDO1TDO2SLC6A4 | |
| SCHEMBL7460123 | 0.82 | IDO1 (0.51) | IDO1TDO2PPARGPPARAPGR | |
| SCHEMBL7471025 | 0.80 | F2 (0.41) | IDO1TDO2 | |
| SCHEMBL7470980 | 0.80 | SLC6A4 (0.39) | IDO1TDO2ACP3PGRSLC6A2 | |
| SCHEMBL7461086 | 0.80 | CASR (0.42) | — | |
| SCHEMBL7455793 | 0.77 | SRD5A2 (0.39) | IDO1TDO2PPARGPPARASLC6A4 | |
| SCHEMBL7470957 | 0.77 | IDO1 (0.43) | IDO1TDO2ACP3PPARGPPARA | |
| SCHEMBL7465983 | 0.76 | IDO1 (0.57) | IDO1TDO2ACP3PPARGPPARA | |
| SCHEMBL7460080 | 0.75 | IDO1 (0.49) | IDO1TDO2PPARGPPARASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244617-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-10-02 | — | — | EP | claimed |
| WO-2001047875-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-07-05 | — | — | WO | claimed |