Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 17/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462527 | 0.94 | PDE5A (0.64) | PDE5ACLK4MEN1KMT2AALDH1A1 | |
| SCHEMBL7470372 | 0.85 | PDE5A (0.52) | PDE5ACLK4MEN1KMT2AALDH1A1 | |
| SCHEMBL7470018 | 0.85 | USP10 (0.57) | PDE5AMEN1KMT2AALDH1A1 | |
| SCHEMBL7468592 | 0.85 | PDE5A (0.52) | PDE5ACLK4MEN1KMT2AALDH1A1 | |
| SCHEMBL7469278 | 0.84 | PDE5A (0.70) | PDE5ACLK4MEN1KMT2AALDH1A1 | |
| SCHEMBL7469507 | 0.84 | PDE5A (0.50) | PDE5ACLK4MEN1KMT2AALDH1A1 | |
| SCHEMBL7473397 | 0.80 | PDE5A (0.59) | PDE5ACLK4MEN1KMT2AALDH1A1 | |
| SCHEMBL7473037 | 0.78 | SRC (0.49) | PDE5AMEN1KMT2AALDH1A1 | |
| SCHEMBL7461671 | 0.78 | HTT (0.52) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7471052 | 0.78 | PDE5A (0.82) | PDE5ACLK4MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |