Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 16/20 | 0.82 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.67 |
| ▸ | CLK1 | P49759 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469278 | 0.93 | PDE5A (0.70) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7499068 | 0.90 | PDE5A (1.00) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7467527 | 0.88 | PDE5A (0.64) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7474381 | 0.86 | PDE5A (0.61) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8015683 | 0.85 | PDE5A (1.00) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7548083 | 0.85 | PDE5A (0.80) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7462527 | 0.84 | PDE5A (0.64) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5137740 | 0.83 | PDE5A (1.00) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7501078 | 0.83 | PDE5A (1.00) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2458882 | 0.82 | PDE5A (1.00) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |