Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | SNCA | P37840 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471035 | 1.00 | KDM4E (0.57) | KDM4ESNCALMNAMAPTCYP1A2 | |
| SCHEMBL7464328 | 0.83 | KDM4E (0.64) | KDM4ELMNAMAPTCYP1A2THRB | |
| Chlorzoxazone SCHEMBL35177 | 0.78 | KDM4E (0.70) | KDM4ELMNAMAPTCYP1A2THRB | |
| SCHEMBL8635794 | 0.78 | KDM4E (0.57) | KDM4ESNCALMNAMAPTCYP1A2 | |
| SCHEMBL8635797 | 0.78 | KDM4E (0.57) | KDM4ESNCALMNAMAPTCYP1A2 | |
| SCHEMBL7471770 | 0.78 | GAA (0.54) | KDM4ESNCASMN1; SMN2CASP3SENP7 | |
| SCHEMBL7471766 | 0.78 | GAA (0.54) | KDM4ESNCASMN1; SMN2CASP3SENP7 | |
| SCHEMBL9338919 | 0.77 | KDM4E (0.50) | KDM4ESNCALMNAMAPTCYP1A2 | |
| SCHEMBL7472176 | 0.77 | SNCA (0.62) | KDM4ESNCALMNAMAPTPSMB8 | |
| SCHEMBL12545773 | 0.77 | KDM4E (0.64) | KDM4ESNCALMNAMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771796-B1 | Substituted S-triazines and process for their preparation | AGFA GEVAERT (BE) | 2002-06-19 | — | — | EP | disclosed |
| EP-0771796-A1 | Substituted S-triazines and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-07 | — | — | EP | disclosed |