Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472170 | 1.00 | SNCA (0.62) | SNCAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6421503 | 0.85 | SNCA (0.64) | SNCAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6421501 | 0.85 | SNCA (0.64) | SNCAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL223564 | 0.81 | HDAC3 (0.56) | SNCAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL26467450 | 0.81 | SNCA (0.79) | SNCAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL26467439 | 0.80 | SNCA (0.64) | SNCAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7471770 | 0.80 | GAA (0.54) | SNCAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7471766 | 0.80 | GAA (0.54) | SNCAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28029680 | 0.79 | HDAC3 (0.54) | SNCAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8718548 | 0.78 | HDAC3 (0.54) | SNCAHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771796-B1 | Substituted S-triazines and process for their preparation | AGFA GEVAERT (BE) | 2002-06-19 | — | — | EP | disclosed |
| EP-0771796-A1 | Substituted S-triazines and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-07 | — | — | EP | disclosed |