Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 17/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CLK1 | P49759 | 2/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.52 |
| ▸ | CLK2 | P49760 | 1/20 | 0.49 |
| ▸ | CLK3 | P49761 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467527 | 0.93 | PDE5A (0.64) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7471052 | 0.86 | PDE5A (0.82) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7469507 | 0.85 | PDE5A (0.50) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7470174 | 0.81 | HTT (0.57) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7469278 | 0.80 | PDE5A (0.70) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7461202 | 0.80 | PDE5A (0.53) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7470372 | 0.79 | PDE5A (0.52) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL16997374 | 0.77 | PDE5A (0.78) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7499068 | 0.77 | PDE5A (1.00) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11852402 | 0.76 | PDE5A (0.64) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169320-A4 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG CHEM INVESTMENT LTD (KR) | 2002-10-30 | — | — | EP | disclosed |
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |
| EP-1169320-A1 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG Chem Investment, Ltd. (KR) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000064891-A1 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2000-11-02 | — | — | WO | disclosed |