Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ELANE | P08246 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL641903 | 0.91 | POLB (0.62) | POLBSMN1; SMN2TDP1NPC1ELANE | |
| SCHEMBL31237097 | 0.91 | POLB (0.62) | POLBSMN1; SMN2TDP1NPC1ELANE | |
| SCHEMBL7471305 | 0.89 | LMNA (0.54) | POLBSMN1; SMN2TDP1NPC1LMNA | |
| SCHEMBL7471861 | 0.85 | TRPV1 (0.56) | ELANELMNACYP4F2CYP4A11TRPM8 | |
| SCHEMBL7467811 | 0.85 | TDP1 (0.52) | TDP1NPC1ELANEADRB2ADRB1 | |
| SCHEMBL27430945 | 0.84 | LMNA (0.55) | POLBSMN1; SMN2TDP1NPC1LMNA | |
| SCHEMBL7472353 | 0.84 | KDM4E (0.56) | SMN1; SMN2NPC1LMNACYP4F2CYP4A11 | |
| SCHEMBL7473301 | 0.84 | CYP4F2 (0.61) | SMN1; SMN2NPC1LMNACYP4F2CYP4A11 | |
| SCHEMBL7470029 | 0.83 | KMT2A (0.58) | POLBSMN1; SMN2NPC1LMNAADRB2 | |
| SCHEMBL7471216 | 0.83 | MAPT (0.54) | POLBSMN1; SMN2NPC1LMNACYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859774-B1 | SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES | BAYER AG (DE) | 2002-04-03 | — | — | EP | disclosed |
| EP-0859774-A1 | SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES | BAYER AG (DE) | 1998-08-26 | — | — | EP | disclosed |