Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 17/20 | 0.52 |
| ▸ | CTSS | P25774 | 17/20 | 0.51 |
| ▸ | CTSK | P43235 | 10/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.49 |
| ▸ | PREP | P48147 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7539083 | 0.88 | CTSL (0.55) | CTSLCTSSCTSKCTSB | |
| SCHEMBL7531795 | 0.86 | CTSL (0.69) | CTSLCTSSCTSKCTSB | |
| SCHEMBL5529602 | 0.85 | CTSL (0.53) | CTSLCTSSCTSKCTSB | |
| SCHEMBL5518263 | 0.85 | CTSL (0.58) | CTSLCTSSCTSKCTSB | |
| SCHEMBL7539158 | 0.85 | CTSL (0.55) | CTSLCTSSCTSKCTSB | |
| SCHEMBL5534179 | 0.84 | CTSL (0.54) | CTSLCTSSCTSKCTSB | |
| SCHEMBL5534161 | 0.84 | CTSL (0.54) | CTSLCTSSCTSKCTSB | |
| SCHEMBL5525335 | 0.84 | CTSL (0.69) | CTSLCTSSCTSKCTSB | |
| SCHEMBL5530441 | 0.84 | CTSL (0.69) | CTSLCTSSCTSKCTSB | |
| SCHEMBL5526563 | 0.83 | CTSL (0.74) | CTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178958-A2 | N-CYANOMETHYL AMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000055125-A2 | N-CYANOMETHYL AMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |