Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 3/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473126 | 0.90 | GPR119 (0.47) | LSSGPR119L3MBTL3MAPTALDH1A1 | |
| SCHEMBL7461457 | 0.90 | GPR119 (0.50) | GPR119L3MBTL3ALDH1A1HPGDDPP4 | |
| Hydrochloric Acid SCHEMBL7473820 | 0.81 | GPR119 (0.51) | LSSGPR119L3MBTL3ALDH1A1HPGD | |
| SCHEMBL7475656 | 0.81 | GPR119 (0.47) | LSSGPR119L3MBTL3ALDH1A1HPGD | |
| SCHEMBL7471264 | 0.80 | GPR119 (0.48) | GPR119L3MBTL3ALDH1A1HPGDDPP4 | |
| SCHEMBL7473064 | 0.80 | DRD4 (0.49) | LSSMAPTALDH1A1SMN1; SMN2DPP4 | |
| SCHEMBL8102276 | 0.79 | GPR119 (0.48) | LSSGPR119L3MBTL3ALDH1A1HPGD | |
| SCHEMBL7473019 | 0.79 | GPR119 (0.48) | LSSGPR119L3MBTL3ALDH1A1HPGD | |
| SCHEMBL7472799 | 0.79 | GPR119 (0.46) | LSSGPR119L3MBTL3MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL7471808 | 0.78 | GPR119 (0.48) | GPR119L3MBTL3ALDH1A1HPGDDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650476-B1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMA CO LTD (JP) | 2002-06-26 | — | — | EP | disclosed |
| US-6136826-A | AMINOPIPERIDINE COMPOUNDS SUBSTITUTED WITH ALKANOYL | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| US-5656642-A | Peripheral vasodilating agent containing piperidine derivative as active ingredient | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |
| WO-1994022826-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-13 | — | — | WO | disclosed |