Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 10/20 | 0.49 |
| ▸ | MMP3 | P08254 | 10/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15130754 | 0.93 | F2 (0.51) | MMP1MMP3F2F10PRSS1 | |
| SCHEMBL15130652 | 0.89 | F2 (0.54) | MMP1MMP3F2F10PRSS1 | |
| SCHEMBL19965194 | 0.88 | F2 (0.48) | MMP1MMP3F2F10PRSS1 | |
| SCHEMBL28938876 | 0.88 | F2 (0.48) | MMP1MMP3F2F10PRSS1 | |
| SCHEMBL21165916 | 0.88 | F2 (0.53) | MMP1MMP3F2F10PRSS1 | |
| SCHEMBL19965191 | 0.86 | F2 (0.46) | MMP1MMP3F2F10PRSS1 | |
| SCHEMBL8430545 | 0.86 | F2 (0.49) | MMP1MMP3F2F10PRSS1 | |
| SCHEMBL7349860 | 0.86 | F2 (0.49) | MMP1MMP3F2F10PRSS1 | |
| SCHEMBL17770856 | 0.85 | F2 (0.48) | MMP1MMP3F2F10PRSS1 | |
| SCHEMBL12494278 | 0.85 | F2 (0.48) | MMP1MMP3F2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815084-A1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | THE PROCTER & GAMBLE COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996029313-A1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | THE PROCTER & GAMBLE COMPANY (US) | 1996-09-26 | — | — | WO | disclosed |