Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPSE | Q9Y251 | 5/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465986 | 0.84 | KMT2A (0.50) | KMT2AHPSEMAOBTP53USP2 | |
| Hydrochloric Acid SCHEMBL7467353 | 0.75 | MAPT (0.53) | MAPK1MAPT | |
| Hydrochloric Acid SCHEMBL7471438 | 0.75 | KDM4E (0.45) | L3MBTL1NAMPT | |
| SCHEMBL7466190 | 0.71 | EGFR (0.43) | KMT2ATP53MAPT | |
| SCHEMBL14542954 | 0.70 | MAPT (0.44) | KMT2AHPSEUSP2ATMMAPK1 | |
| SCHEMBL7472023 | 0.70 | HRAS (0.51) | KMT2AHPSEMAPK1MAPT | |
| SCHEMBL8603119 | 0.70 | SPHK2 (0.42) | — | |
| Hydrochloric Acid SCHEMBL7469233 | 0.70 | MAPT (0.50) | KMT2AHPSEATMMAPK1MAPT | |
| SCHEMBL31612382 | 0.69 | ATM (0.61) | KMT2AHPSEMAOBTP53ATM | |
| SCHEMBL5561204 | 0.69 | RHEB (0.41) | KMT2ATP53ATMMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |