Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | MMP9 | P14780 | 3/20 | 0.42 |
| ▸ | MMP8 | P22894 | 3/20 | 0.42 |
| ▸ | MMP13 | P45452 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470394 | 0.84 | MAPT (0.47) | KMT2AMAPTMEN1POLBMMP2 | |
| SCHEMBL7471952 | 0.84 | KMT2A (0.44) | KMT2AMAPTGAAMAPK1HPSE | |
| SCHEMBL5559865 | 0.83 | MEN1 (0.47) | KMT2AMAPTMEN1POLBMMP2 | |
| SCHEMBL5333969 | 0.80 | CHEK2 (0.47) | KMT2AMAPTMEN1POLBMMP2 | |
| SCHEMBL7469008 | 0.79 | MAPT (0.50) | KMT2AMAPTMEN1POLBMMP2 | |
| SCHEMBL7464254 | 0.79 | MAPT (0.47) | KMT2AMAPTMEN1POLBMMP2 | |
| SCHEMBL7468134 | 0.78 | MAPT (0.49) | KMT2AMAPTMEN1POLBMMP2 | |
| SCHEMBL7470426 | 0.77 | MAPT (0.49) | KMT2AMAPTMEN1POLBMMP2 | |
| SCHEMBL7464777 | 0.76 | MAPT (0.49) | KMT2AMAPTMEN1POLBMMP2 | |
| SCHEMBL7463992 | 0.76 | MAPT (0.49) | KMT2AMAPTMEN1POLBMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |