Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRAS | P01112 | 11/20 | 0.39 |
| ▸ | ESR1 | P03372 | 11/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471663 | 0.91 | HRAS (0.46) | HRASESR1ESR2SMN1; SMN2POLB | |
| SCHEMBL7470676 | 0.87 | HRAS (0.39) | HRASESR1ESR2POLBEGFR | |
| Hydrochloric Acid SCHEMBL7473851 | 0.86 | HRAS (0.44) | HRASESR1ESR2CYP2C19GFER | |
| SCHEMBL7472474 | 0.85 | HRAS (0.42) | HRASESR1ESR2EGFR | |
| SCHEMBL7476267 | 0.85 | HRAS (0.39) | HRASESR1ESR2SMN1; SMN2POLB | |
| SCHEMBL7467723 | 0.85 | EGFR (0.34) | HRASESR1ESR2POLBEGFR | |
| SCHEMBL7470847 | 0.84 | HRAS (0.39) | HRASESR1ESR2POLBEGFR | |
| SCHEMBL7459798 | 0.84 | HRAS (0.38) | HRASESR1ESR2POLBEGFR | |
| SCHEMBL7463241 | 0.82 | MAPT (0.42) | HRASESR1ESR2CYP2C19GFER | |
| SCHEMBL7472023 | 0.82 | HRAS (0.51) | HRASESR1ESR2POLBEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |