Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRAS | P01112 | 12/20 | 0.42 |
| ▸ | ESR1 | P03372 | 12/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 12/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ESRRG | P62508 | 3/20 | 0.35 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.35 |
| ▸ | ESRRB | O95718 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471663 | 0.91 | HRAS (0.46) | HRASESR1ESR2EGFRMEN1 | |
| Hydrochloric Acid SCHEMBL7469529 | 0.86 | HRAS (0.55) | HRASESR1ESR2EGFR | |
| Hydrochloric Acid SCHEMBL7474731 | 0.86 | HRAS (0.43) | HRASESR1ESR2 | |
| Hydrochloric Acid SCHEMBL7476431 | 0.86 | HRAS (0.47) | HRASESR1ESR2CNR1EGFR | |
| SCHEMBL7472043 | 0.85 | HRAS (0.39) | HRASESR1ESR2EGFR | |
| Hydrochloric Acid SCHEMBL7461628 | 0.85 | HRAS (0.54) | HRASESR1ESR2 | |
| Hydrochloric Acid SCHEMBL7470751 | 0.83 | HRAS (0.55) | HRASESR1ESR2EGFR | |
| Hydrochloric Acid SCHEMBL7465588 | 0.83 | HRAS (0.46) | HRASESR1ESR2EGFRPRSS12 | |
| SCHEMBL7470847 | 0.82 | HRAS (0.39) | HRASESR1ESR2EGFRMEN1 | |
| SCHEMBL7470676 | 0.82 | HRAS (0.39) | HRASESR1ESR2EGFRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |