⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1706184 | 0.76 | — | — | |
| SCHEMBL1237694 | 0.75 | — | — | |
| SCHEMBL4015171 | 0.69 | — | — | |
| SCHEMBL4227514 | 0.68 | — | — | |
| SCHEMBL18795323 | 0.67 | — | — | |
| SCHEMBL17527710 | 0.63 | — | — | |
| SCHEMBL3406429 | 0.63 | — | — | |
| SCHEMBL15488836 | 0.61 | — | — | |
| SCHEMBL5180094 | 0.61 | ALDH1A1 (0.32) | — | |
| SCHEMBL6987370 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013302-A1 | SYSTEM AND METHOD FOR DETERMINING ONSET AND DISEASE PROGRESSION | Respiration Scan Ltd (IL) | 2022-06-22 | — | — | EP | disclosed |
| WO-2021028928-A1 | SYSTEM AND METHOD FOR DETERMINING ONSET AND DISEASE PROGRESSION | RESPIRATION SCAN LTD (IL) | 2021-02-18 | — | — | WO | disclosed |
| WO-2016007736-A1 | IMIDAZOPYRAZINES AS LSD1 INHIBITORS | INCYTE CORPORATION (US) | 2016-01-14 | — | — | WO | disclosed |
| EP-2429295-A1 | ARYL, HETEROARYL, AND HETEROCYCLE SUBSTITUTED TETRAHYDROISOQUINOLINES AND USE THEREOF | Albany Molecular Research, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132437-A1 | ARYL, HETEROARYL, AND HETEROCYCLE SUBSTITUTED TETRAHYDROISOQUINOLINES AND USE THEREOF | ALBANY MOLECULAR RESEARCH, INC. (US) | 2010-11-18 | — | — | WO | disclosed |
| EP-1742627-A4 | PDE4B INHIBITORS AND USES THEREFOR | PLEXXIKON INC (US) | 2009-08-26 | — | — | EP | disclosed |
| WO-2009094205-A2 | 3-ARYL-6-ARYL-7H-[1,2,4]TRIAZOLO[3,4-B][1,3,4]THIADIAZINES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | CYTOVIA, INC. (US) | 2009-07-30 | — | — | WO | disclosed |
| EP-2024365-A2 | PREPARATION AND UTILITY OF SUBSTITUTED IMIDAZOPYRIDINE COMPOUNDS WITH HYPNOTIC EFFECTS | Auspex Pharmaceuticals Inc. (US) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007143468-A2 | PREPARATION AND UTILITY OF SUBSTITUTED IMIDAZOPYRIDINE COMPOUNDS WITH HYPNOTIC EFFECTS | AUSPEX PHARMACEUTICALS, INC. (US) | 2007-12-13 | — | — | WO | disclosed |
| EP-1742627-A2 | PDE4B INHIBITORS AND USES THEREFOR | PLEXXIKON, INC. (US) | 2007-01-17 | — | — | EP | disclosed |
| WO-2006078287-A9 | PDE4B INHIBITORS AND USES THEREFOR | PLEXXIKON INC (US) | 2006-08-31 | — | — | WO | disclosed |
| WO-2006078287-A2 | PDE4B INHIBITORS AND USES THEREFOR | PLEXXIKON, INC. (US) | 2006-07-27 | — | — | WO | disclosed |