Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.50 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.49 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3081576 | 0.83 | ARSA (0.56) | ESR2ESR1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL17384169 | 0.79 | HPRT1 (0.56) | ESR2CYP1A1CYP1A2CYP1B1TDP1 | |
| SCHEMBL17384172 | 0.79 | HPRT1 (0.56) | ESR2CYP1A1CYP1A2CYP1B1TDP1 | |
| SCHEMBL18327130 | 0.79 | DYRK1A (0.69) | NPSR1RXFP1ESR2CSNK2A1ESR1 | |
| SCHEMBL29401241 | 0.76 | NPSR1 (1.00) | NPSR1RXFP1ESR2CSNK2A1ESR1 | |
| SCHEMBL29369247 | 0.76 | NPSR1 (1.00) | NPSR1RXFP1ESR2CSNK2A1ESR1 | |
| SCHEMBL4420540 | 0.76 | NPSR1 (1.00) | NPSR1RXFP1ESR2CSNK2A1ESR1 | |
| SCHEMBL8074166 | 0.76 | ESR2 (0.60) | NPSR1RXFP1ESR2CSNK2A1ESR1 | |
| Hydrochloric Acid SCHEMBL30777912 | 0.75 | NPSR1 (0.96) | NPSR1RXFP1ESR2CSNK2A1ESR1 | |
| SCHEMBL4444894 | 0.74 | KDM4E (0.63) | NPSR1RXFP1ESR2CSNK2A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097156-B1 | PHTOCHROMIC BENZOPYRANO-FUSED NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2002-10-02 | — | — | EP | disclosed |
| US-6022495-A | FOR OPTICAL APPLICATIONS | TRANSITIONS OPTICAL, INC. (US) | 2000-02-08 | — | — | US | disclosed |