Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | PKLR | P30613 | 2/20 | 0.50 |
| ▸ | GALNT2 | Q10471 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.50 |
| ▸ | GALNT1 | Q10472 | 1/20 | 0.50 |
| ▸ | GALNT3 | Q14435 | 1/20 | 0.50 |
| ▸ | GALNT10 | Q86SR1 | 1/20 | 0.50 |
| ▸ | GALNT13 | Q8IUC8 | 1/20 | 0.50 |
| ▸ | GALNT6 | Q8NCL4 | 1/20 | 0.50 |
| ▸ | GALNT14 | Q96FL9 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18327134 | 0.84 | DYRK1A (0.67) | DYRK1AGAALMNAMAPTMEN1 | |
| SCHEMBL26779869 | 0.81 | ESR2 (0.64) | ESR2NPSR1RXFP1LMNAPPARG | |
| SCHEMBL7987277 | 0.78 | ESR2 (0.70) | ESR2GAANPSR1RXFP1PKLR | |
| SCHEMBL30880452 | 0.77 | ESR2 (0.57) | ESR2GAANPSR1RXFP1LMNA | |
| SCHEMBL9270555 | 0.77 | DYRK1A (0.59) | DYRK1AGAALMNAMAPTMEN1 | |
| SCHEMBL18327135 | 0.77 | DYRK1A (0.64) | ESR2DYRK1AGAALMNAMAPT | |
| SCHEMBL7472194 | 0.76 | NPSR1 (0.61) | ESR2DYRK1ANPSR1RXFP1LMNA | |
| SCHEMBL29853705 | 0.75 | ESR2 (0.66) | ESR2NPSR1RXFP1PKLRGALNT2 | |
| SCHEMBL6825266 | 0.75 | ESR2 (1.00) | ESR2GAAKDM4EHPGDHSD17B10 | |
| SCHEMBL30629209 | 0.75 | ESR2 (0.66) | ESR2NPSR1RXFP1PKLRGALNT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6149841-A | COMPOUNDS SUCH AS 3,3-BIS(4-METHOXYPHENYL)-13-OXO-3,13-DIHYDROBENZO(B)PYRANO -(4',3':6,7)NAPHTHO(2,1-B)PYRAN; ACCEPTABLE FADE RATE WITHOUT THE ADDITION OF ACIDS OR BASES AND AN ACCEPTABLE COLORATION RATE AT ROOM TEMPERATURE | PPG INDUSTRIES OHIO, INC. (US) | 2000-11-21 | — | — | US | disclosed |