Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962258 | 0.95 | CA12 (0.33) | CA12CA1CA9CA2 | |
| SCHEMBL6968769 | 0.90 | TSHR (0.32) | TSHRCA12CA1CA9CA2 | |
| SCHEMBL1796805 | 0.89 | CA12 (0.36) | DNM1LMNATSHRCA12CA1 | |
| SCHEMBL6973884 | 0.84 | CA12 (0.33) | CA12CA1CA9CA2 | |
| SCHEMBL1793940 | 0.82 | CA12 (0.33) | CA12CA1CA9CA2 | |
| SCHEMBL5449385 | 0.80 | TSHR (0.36) | LMNATSHRCA12CA1CA9 | |
| SCHEMBL1794717 | 0.79 | DNM1 (0.46) | DNM1LMNATSHRCA12CA1 | |
| SCHEMBL6975507 | 0.79 | CA12 (0.35) | TSHRCA12CA1CA9CA2 | |
| SCHEMBL1794184 | 0.79 | DNM1 (0.46) | DNM1LMNATSHRCA12CA1 | |
| SCHEMBL1795019 | 0.79 | DNM1 (0.46) | DNM1LMNATSHRCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | claimed |
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-5852011-A | Benzimidazole derivatives | MITSUI CHEMICALS, INC. (JP) | 1998-12-22 | — | — | US | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-4281127-A | USEFUL AS ANTIALLERGENS | HOFFMANN-LA ROCHE INC. (US) | 1981-07-28 | — | — | US | disclosed |