Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 20/20 | 0.59 |
| ▸ | PLA2G1B | P04054 | 8/20 | 0.59 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.55 |
| ▸ | PLA2G5 | P39877 | 3/20 | 0.55 |
| ▸ | PLA2G2E | Q9NZK7 | 2/20 | 0.54 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.54 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.54 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.54 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.54 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.54 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.54 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL819781 | 0.90 | PLA2G2A (0.68) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL6695470 | 0.89 | PLA2G2A (0.67) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL6695479 | 0.89 | PLA2G2A (0.67) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL29862311 | 0.89 | PLA2G2A (0.65) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL818265 | 0.89 | PLA2G2A (0.65) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL817716 | 0.88 | PLA2G2A (0.52) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL29967001 | 0.88 | PLA2G2A (0.66) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL818358 | 0.88 | PLA2G2A (0.66) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL7953561 | 0.88 | PLA2G2A (0.52) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL29862858 | 0.88 | PLA2G2A (0.52) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259260-A1 | COMBINATION THERAPY FOR THE TREATMENT OF INFLAMMATORY AND RESPIRATORY DISEASES | ELI LILLY AND COMPANY (US) | 2002-11-27 | — | — | EP | claimed |
| WO-2001049323-A1 | COMBINATION THERAPY FOR THE TREATMENT OF INFLAMMATORY AND RESPIRATORY DISEASES | ELI LILLY AND COMPANY (US) | 2001-07-12 | — | — | WO | claimed |