Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.31 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8742977 | 0.95 | NPSR1 (0.36) | NPSR1GAAMAPTLMNACA12 | |
| SCHEMBL7467560 | 0.94 | NPSR1 (0.38) | NPSR1GAAMAPTLMNACA12 | |
| SCHEMBL7477246 | 0.91 | NPSR1 (0.39) | NPSR1GAAMAPTLMNACA12 | |
| SCHEMBL7471274 | 0.91 | NPSR1 (0.38) | NPSR1GAAMAPTLMNACA12 | |
| SCHEMBL7471625 | 0.90 | NPSR1 (0.41) | NPSR1GAAMAPTLMNACA12 | |
| SCHEMBL7471149 | 0.88 | NPSR1 (0.39) | NPSR1GAAMAPTLMNACA12 | |
| SCHEMBL8742735 | 0.87 | NPSR1 (0.40) | NPSR1GAAMAPTLMNACA12 | |
| SCHEMBL7466648 | 0.86 | NPSR1 (0.45) | NPSR1GAAMAPTLMNACA12 | |
| Trifluoroacetic Acid SCHEMBL8592809 | 0.86 | NPSR1 (0.36) | NPSR1GAAMAPTLMNACA12 | |
| SCHEMBL7476887 | 0.86 | NPSR1 (0.39) | NPSR1GAAMAPTLMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687251-B1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI SYNTHELABO (FR) | 2002-02-27 | — | — | EP | disclosed |
| WO-1995018105-A1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI (FR) | 1995-07-06 | — | — | WO | disclosed |