Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 7/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 7/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472477 | 1.00 | CHRNB2 (0.48) | CHRNB2CHRNA3CHRNB4CHRNA7CHRNA4 | |
| Oxalic Acid SCHEMBL7994348 | 0.92 | CHRNB2 (0.44) | CHRNB2CHRNA3 | |
| Oxalic Acid SCHEMBL7994351 | 0.92 | CHRNB2 (0.44) | CHRNB2CHRNA3 | |
| SCHEMBL7423822 | 0.91 | CHRNB2 (0.50) | CHRNB2CHRNA3 | |
| SCHEMBL7423827 | 0.91 | CHRNB2 (0.50) | CHRNB2CHRNA3 | |
| Oxalic Acid SCHEMBL7423054 | 0.83 | CHRNB2 (0.44) | CHRNB2CHRNA3 | |
| Oxalic Acid SCHEMBL7414834 | 0.83 | CHRNB2 (0.44) | CHRNB2CHRNA3 | |
| SCHEMBL7994340 | 0.81 | CHRNB2 (0.49) | CHRNB2CHRNA3 | |
| Oxalic Acid SCHEMBL8009465 | 0.74 | CHRNB2 (0.43) | CHRNB2CHRNA3 | |
| SCHEMBL7424304 | 0.72 | CHRNB2 (0.40) | CHRNB2CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022868-A | TREATING DISEASES IN THE CENTRAL NERVOUS SYSTEM RELATED TO MALFUNCTIONING OF THE NICOTINIC CHOLINERGIC SYSTEM. | NOVO NORDISK ALS (DK) | 2000-02-08 | — | — | US | claimed |
| US-6022868-A | TREATING DISEASES IN THE CENTRAL NERVOUS SYSTEM RELATED TO MALFUNCTIONING OF THE NICOTINIC CHOLINERGIC SYSTEM. | NOVO NORDISK ALS (DK) | 2000-02-08 | — | — | US | disclosed |
| EP-0842172-A1 | NOVEL SUBSTITUTED AZACYCLIC OR AZABICYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997001556-A1 | NOVEL SUBSTITUTED AZACYCLIC OR AZABICYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1997-01-16 | — | — | WO | disclosed |