Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 11/20 | 0.35 |
| ▸ | CTSS | P25774 | 11/20 | 0.35 |
| ▸ | CTSK | P43235 | 11/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6475013 | 0.91 | CTSL (0.34) | CTSLCTSSCTSK | |
| SCHEMBL7464591 | 0.90 | CTSL (0.37) | CTSLCTSSCTSK | |
| SCHEMBL7469401 | 0.84 | CTSL (0.36) | CTSLCTSSCTSK | |
| SCHEMBL6477014 | 0.84 | CTSL (0.36) | CTSLCTSSCTSK | |
| SCHEMBL7458638 | 0.83 | CTSL (0.34) | CTSLCTSSCTSK | |
| SCHEMBL6475802 | 0.81 | CTSL (0.42) | CTSLCTSSCTSK | |
| SCHEMBL6475781 | 0.81 | CTSL (0.36) | CTSLCTSSCTSK | |
| SCHEMBL7462606 | 0.80 | CTSL (0.32) | CTSLCTSSCTSK | |
| SCHEMBL7464082 | 0.79 | — | — | |
| SCHEMBL7472917 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178986-A2 | FURANONE DERIVATIVES AS INHIBITORS OF CATHEPSIN S | Medivir UK Ltd (GB) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000069855-A2 | FURANONE DERIVATIVES AS INHIBITORS OF CATHEPSIN S | MEDIVIR UK LIMITED (GB) | 2000-11-23 | — | — | WO | disclosed |