Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470791 | 0.89 | GRIN1 (0.58) | GRIN1 | |
| SCHEMBL7460279 | 0.87 | GRIN1 (0.63) | GRIN1 | |
| SCHEMBL7590619 | 0.87 | GRIN1 (0.63) | GRIN1 | |
| SCHEMBL8484806 | 0.77 | GRIN1 (0.64) | GRIN1 | |
| SCHEMBL7472962 | 0.76 | GRIN1 (0.77) | GRIN1 | |
| SCHEMBL8489104 | 0.76 | GRIN1 (0.53) | GRIN1 | |
| SCHEMBL7467247 | 0.74 | GRIN1 (1.00) | GRIN1 | |
| SCHEMBL7466031 | 0.73 | GRIN1 (0.67) | GRIN1 | |
| SCHEMBL7586603 | 0.73 | GRIN1 (0.79) | GRIN1 | |
| SCHEMBL7465495 | 0.72 | GRIN1 (1.00) | GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783495-B1 | QUINOXALINE DERIVATIVES USEFUL IN THERAPY | PFIZER LTD (GB) | 2002-02-27 | — | — | EP | disclosed |
| WO-1996009295-A1 | QUINOXALINE DERIVATIVES USEFUL IN THERAPY | PFIZER LIMITED (GB) | 1996-03-28 | — | — | WO | disclosed |