Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 20/20 | 0.63 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460279 | 1.00 | GRIN1 (0.63) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8484806 | 0.89 | GRIN1 (0.64) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL7470791 | 0.87 | GRIN1 (0.58) | GRIN1 | |
| SCHEMBL7472873 | 0.87 | GRIN1 (0.58) | GRIN1 | |
| SCHEMBL7465495 | 0.77 | GRIN1 (1.00) | GRIN1 | |
| SCHEMBL7467247 | 0.76 | GRIN1 (1.00) | GRIN1 | |
| SCHEMBL8489104 | 0.76 | GRIN1 (0.53) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL7586603 | 0.75 | GRIN1 (0.79) | GRIN1 | |
| SCHEMBL8490654 | 0.73 | GRIN1 (0.58) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| Uk-240455 SCHEMBL6906418 | 0.73 | GRIN1 (0.86) | GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784973-B1 | Quinoxaline derivatives for treating tinnitus | PFIZER (US) | 2002-02-06 | — | — | EP | claimed |
| US-5840723-A | Quinoxaline derivatives for treating tinnitus | PFIZER INC. (US) | 1998-11-24 | — | — | US | claimed |
| EP-0784973-A2 | Quinoxaline derivatives for treating tinnitus | PFIZER INC. (US) | 1997-07-23 | — | — | EP | claimed |
| EP-0784973-B1 | Quinoxaline derivatives for treating tinnitus | PFIZER (US) | 2002-02-06 | — | — | EP | disclosed |
| US-5840723-A | Quinoxaline derivatives for treating tinnitus | PFIZER INC. (US) | 1998-11-24 | — | — | US | disclosed |
| EP-0784973-A2 | Quinoxaline derivatives for treating tinnitus | PFIZER INC. (US) | 1997-07-23 | — | — | EP | disclosed |