SCHEMBL7472979

SCHEMBL7472979

Cc1ccc(S(=O)(=O)n2cc(C[C@H]3CCCN3C)c3cc(Br)ccc32)cc1

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 20/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7472988 1.00 HTR6 (0.75) HTR6
SCHEMBL8209793 0.88 HTR6 (0.75) HTR6
SCHEMBL8209790 0.88 HTR6 (0.75) HTR6
SCHEMBL8208538 0.83 HTR6 (0.68) HTR6
SCHEMBL8208542 0.83 HTR6 (0.68) HTR6
SCHEMBL8483886 0.80 HTR6 (0.66) HTR6
SCHEMBL8208595 0.80 HTR6 (0.82) HTR6
SCHEMBL8213978 0.80 HTR6 (0.82) HTR6
SCHEMBL8209383 0.79 HTR6 (0.79) HTR6
SCHEMBL8209518 0.79 HTR6 (1.00) HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975594-B1 PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES PFIZER LTD (GB) 2002-09-18 EP disclosed
US-6281357-B1 HEADACHE THERAPY PFIZER INC 2001-08-28 US disclosed
EP-0975594-A1 PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES Pfizer Limited (GB) 2000-02-02 EP disclosed
WO-1999002493-A1 PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES PFIZER LIMITED (GB) 1999-01-21 WO disclosed